Morocco also make one change from their defeat to Portugal, with Benatia dropping to the bench in favour of Saiss, who lines up alongside da Costa at centre-back.
Spain make only one change to the side that started in their victory against Iran, with Thiago coming into the side in place of Vazquez, who drops to the bench.
Morocco XI (4-2-3-1): Munir Mohamedi; Nabil Dirar, Manuel da Costa, Romain Saiss, Achraf Hakimi; Karim El Ahmadi, Moubarak Boussoufa; Nordin Amrabat, Younes Belhanda, Hakim Ziyech; Khalid Boutaib.
Spain substitutes: Cesar Azpilicueta, Saul Niguez, Alvaro Odriozola, Lucas Vazquez, Kepa Arrizabalaga, Nacho Monreal, Iago Aspas, Nacho, Koke, Rodrigo Moreno, Jose Reina, Marco Asensio.
Spain XI (4-2-3-1): David De Gea; Daniel Carvajal, Gerard Pique, Sergio Ramos, Jordi Alba; Sergio Busquets, Thiago Alcantara; David Silva, Andres Iniesta, Isco; Diego Costa.