Arsenal makes six changes to the starting line-up from that 2-2 draw against CSKA Moscow during the week. Pierre Emerick-Aubameyang returns to the side after being ineligible to feature in European competition. Calum Chambers and Rob Holding replace Hector Bellerin and Laurent Koscielny in defence, while Aaron Ramsey, Jack Wilshere and Mesut Ozil are replaced in midfield by Granit Xhaka, Alex Iwobi and Joe Willock.
Arsenal substitutes: Mertesacker, Ospina, Welbeck, Maitland-Niles, Kolasinac, Nelson, Nketiah.
Arsenal XI (4-2-3-1): Cech; Chambers, Mustafi, Holding, Monreal; Elneny, Xhaka; Willock, Iwobi, Aubameyang; Lacazette.
Newcastle United substitutes: Clark, Murphy, Slimani, Hayden, Manquillo, Joselu, Darlow.
Newcastle United XI (4-4-1-1): Dubravka; Yedlin, Lascelles, Lejeune, Dummett; Ritchie, Diame, Shelvey, Kenedy; Perez; Gayle.
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