Arsene Wenger wrings the changes with one eye on Thursday’s Europa League semi-final clash against Atletico Madrid. Opsina replaces Petr Cech in goal, while Koscielny and Bellerin replace Chambers and Holding in defence. Ramsey is in for Joe Willock in midfield and Aubameyang is amongst the substitutes as Welbeck starts in his place.
West Ham substitutes: Jordan Hugill, Patrice Evra, Josh Cullen, Andy Carroll, Chicharito, Adrian, Manuel Lanzini.
West Ham XI (3-4-2-1): Joe Hart; Declan Rice, Angelo Ogbonna, Aaron Cresswell; Pablo Zabaleta, Cheikhou Kouyate, Mark Noble, Arthur Masuaku; Edimilson Fernandes, Joao Mario; Marko Arnautovic.
Arsenal substitutes: Ainsley Maitland-Niles, Per Mertesacker, Rob Holding, Reiss Nelson, Pierre-Emerick Aubameyang, Calum Chambers, Matt Macey.
Arsenal XI (4-2-3-1): David Ospina; Hector Bellerin, Shkodran Mustafi, Laurent Koscielny, Nacho Monreal; Granit Xhaka, Mohamed Elneny; Alex Iwobi, Aaron Ramsey, Danny Welbeck; Alexandre Lacazette
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